Unlock Your True Potential with The Buffie Protocol

A Personalized Path To Lasting Health And Confidence

It's time to reclaim control of your life, and unlock the vibrant, confident you that you've always wanted to be.

If you're tired of the endless cycle of weight loss frustrations, it's time for a change. The Buffie Protocol is different – it's not just about losing weight; it's about regaining control of your health.

Our program combines medically-backed solutions, personalized medications, transformative therapy, and a holistic approach to nutrition and fitness. We understand that weight management is about more than just numbers on a scale; it's about addressing both the physical and emotional aspects of your journey. Say goodbye to quick fixes and hello to lasting results.


With a personalized plan that includes medically-backed solutions, tailored medications, transformative therapy, and a holistic approach to nutrition and fitness, you'll have the tools you need to succeed.

Check out...

How I lost 80 lbs and kept it off

Join me, Dr. David Purselle, and Dr. Measha Dancy for a discussion on how to maintain your weight after getting off of semaglutide.

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Before And After Transformation: 
Witness The Power Of The Buffie Protocol

Are you wondering what real results look like with The Buffie Protocol? Let the visual evidence speak for itself. We're proud to showcase the remarkable transformations of individuals who have embraced this life-changing program. These before and after photos are not just about weight loss; they're about reclaiming health, boosting confidence, and redefining what's possible.

MrsMD's Tailored Weight Loss Journey

Embark on a personalized and empowering weight loss journey with MrsMD. Our program is structured into four steps, each designed to support and guide you toward your health goals with our unique MrsMD touch.

MrsMD's First Step:

Personalized Planning

  • Initial Consultation: Begin with a one-on-one session with your provider to create a customized weight loss plan.  
  • Medication Introduction: 
    Start your journey with MrsMD-approved medications. [Note: We do not accept insurance. We prescribe compounded formulations of Semagludtide or Tirezepatide. 
  • Genetic Insight: Discuss the potential of genetic testing for obesity to personalize your plan further.

MrsMD's Progress Pathway:

Monitoring and Adjustment

  • Baseline Benchmarking: Set your initial markers with necessary labs and scans.
  • Plan Evolution: Regularly update your plan in consultation with your provider.
  • Nutritional Navigation: Get dietary guidance and support from our registered dietitian. 

MrsMD's Continual Care:

Support and Guidance

  • Consistent Consultations:
    Stay on track with continuous support from your healthcare team.
  • Adaptive Strategy: Adjust your treatment plan as needed based on your progress.

MrsMD's Milestone Marker:

Evaluation and Maintenance

  • Progress Analysis: Re-evaluate your achievements through follow-up laboratory studies.
  • Sustainable Success: Discuss your journey and plan for long-term maintenance and well-being.

Conclusion: Begin your transformation with MrsMD. Schedule your first consultation and take a step towards a healthier, more fulfilled you.

Offering Compounded Alternatives for Effective Obesity Treatment

At MrsMD Weight Loss, we understand the challenges patients without insurance coverage face in accessing brand-name medications. To address this, we offer a viable and safe alternative through compounded generic medications tailored explicitly for effective obesity treatment.

These compounded alternatives are carefully prepared to meet the same high efficacy standards as their brand-name counterparts. Our goal is to make obesity treatment accessible and effective for all our patients, regardless of their insurance status.

We adhere to stringent safety protocols and quality checks to ensure that these compounded medications provide a reliable and effective option for those seeking assistance in their weight loss journey. Your health and well-being are our top priorities, and we are committed to offering comprehensive and accessible obesity treatment solutions at MrsMD Weight Loss.

The Buffie Protocol isn't just a program;

It's a life-altering journey towards lasting health and confidence. These before and after images are a testament to the power of personalized solutions, transformative therapy, and a holistic approach to nutrition and fitness.

Join the countless individuals who have unlocked their true potential with The Buffie Protocol. Your own incredible transformation could be just around the corner. Click below to take the first step towards a healthier, happier you.

One-Time Medical Consult Fee $75!
Semaglutide starts at $350 per month
Tirzepatide starts at $500 per month

We can ship to:
AL, CA, CT, DC, FL, GA, IN, LA, MD, MI, MO, NC, NY, OH, TN, TX, and WA

See below for a disclaimer about using compounded medications.

Compounding at MrsMD Weight Loss

We at MrsMD Weight Loss understand the concerns raised regarding the improper compounding of medications. In our commitment to safety and efficacy, we want to address these concerns and assure our clients of our stringent adherence to quality standards.

As outlined by the Obesity Medicine Association, compounding pharmacies are regulated by State Boards of Pharmacy and are expected to comply with Current Good Manufacturing Practice (CGMP) requirements. These pharmacies may also receive compounding accreditation. Clinicians need to verify that the source of anti-obesity medications and their formulations have undergone adequate clinical trial testing for efficacy and safety.

At MrsMD Weight Loss, we take these guidelines seriously. Our compounding pharmacies undergo rigorous verification to meet all safety and efficacy standards. We diligently confirm that these pharmacies are in good standing with their respective State’s Board of Pharmacy and the FDA.

Furthermore, we continuously monitor and compare our data from patients who have been prescribed both brand-name medications and compounded alternatives. Our findings have consistently shown similar and excellent results in both groups, further confirming the effectiveness and safety of our compounded medication options.

Please be assured that at MrsMD Weight Loss, your health and well-being are our utmost priorities. We are dedicated to providing the highest standards of care and medication to assist you in your weight loss journey.

Featured Video:

Dr. David Purselle Demonstrates the shot...

Join Dr. David Purselle as he guides you through the process of administering the Buffie Protocol shot. This informative video will help you understand the procedure and give you the confidence to take control of your health. Dr. Purselle's expertise ensures that you'll be well-prepared for your Buffie Protocol journey.


Frequently Asked Questions

How many times do I inject?

The frequency of injections depends on the specific GLP-1 medication prescribed. Typically, most patients inject once a week. Your physician will provide specific instructions tailored to you.

How often do I need an appointment?

We recommend monthly follow-up appointments to monitor your progress and adjust dosages if necessary.

How many pounds will I lose in a month?

Weight loss varies for each individual based on multiple factors. On average, patients can expect to lose 5- 10lbs per month. However, individual results may vary. We have had some patients lose as much as 30lbs in one month. 

How long do I have to stay on the shots?

The duration varies depending on individual goals and response to the medication. Generally, patients remain on the medication for 4-6 months, after which we reassess.

What's the plan after I get off the shots?

Once you achieve your desired weight or complete the medication course, we'll transition you to a maintenance plan. This includes nutritional guidance, potential supplemental support, and regular check-ups to ensure continued success.

Can I do TMS in a different state?

TMS (Transcranial Magnetic Stimulation) should be administered by certified practitioners. While you can receive TMS treatments in other states, it's important to ensure the facility is licensed and has experienced professionals. We currently offer TMS in our Atlanta, GA, medical clinic.

Can I pay per session for TMS?

Yes, we offer a pay-per-session option for TMS. However, we also have package deals that offer better value for multiple sessions.

Will the shots give me stomach paralysis?

GLP-1 agonist medications can slow stomach emptying, which contributes to feelings of fullness and reduces food intake.  In rare instances the medications can cause stomach paralysis. This usually resolves in a few days if it occurs.

If I have Hypoglycemia, can I take the shots?

If you have a history of hypoglycemia or any other medical conditions, it's essential to discuss this with the physician. While GLP-1 medications can be safe for many individuals with hypoglycemia, individual medical evaluation is necessary.

What states are you currently licensed in?

AL, CA, CT, DC, FL, GA, IN, LA, MD, MI, MO, NC, NY, OH, TN, TX, and WA

Meet Our Team

Buffie Purselle

Founder & CEO

David Purselle, MD, MSCR

Medical Director

Measha Dancy, MD

Internal Medicine

Linda Yatak, MSN, PMHNP-BC

Psychiatric Nurse Practitioner

Chris Weldon

Lead TMS Technician

Brenda Garcia

Patient Care Specialist

Lisette Ramos

Patient Care Supervisor

Omolayo, PA-C

Physician Assistant

Dorinda Ezell, MSN, FNP-C

Family Nurse Practitioner

Join the MrsMD® Weight Loss Support Group

Join Our Journey to Transformation: Become a part of the MrsMD® Weight Loss community, where we conquer challenges, celebrate milestones, and support each other every step of the way. Click 'Join Group' to start your path to a healthier, happier you with friends who care!